Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.44 |
| ▸ | PPARA | Q07869 | 8/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754462 | 0.85 | PPARD (0.61) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL2464883 | 0.82 | PPARD (0.41) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL2468793 | 0.79 | PPARD (0.56) | PPARDFFAR1PPARAPPARGMEN1 | |
| SCHEMBL2467702 | 0.75 | ABCB1 (0.38) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL377186 | 0.74 | PPARA (0.63) | PPARDPPARAPPARGTP53 | |
| SCHEMBL2465204 | 0.74 | PPARD (0.46) | PPARDFFAR1PPARAPPARGMEN1 | |
| SCHEMBL4754485 | 0.72 | PPARD (0.47) | PPARDFFAR1PPARAPPARGMAPT | |
| SCHEMBL1766000 | 0.71 | PPARD (0.40) | PPARDFFAR1PPARAPPARGMEN1 | |
| SCHEMBL6302340 | 0.70 | PPARD (0.74) | PPARDPPARAPPARGMEN1ALDH1A1 | |
| SCHEMBL2466122 | 0.70 | PPARD (0.45) | PPARDFFAR1PPARAPPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |