Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155271 | 0.87 | GPR119 (0.59) | GPR119CNR2L3MBTL1KMT2APANK3 | |
| SCHEMBL4674581 | 0.81 | CNR2 (0.49) | GPR119CNR2L3MBTL1KMT2ADRD2 | |
| SCHEMBL2959440 | 0.81 | CHRM4 (0.66) | GPR119L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4958636 | 0.80 | GPR119 (0.46) | GPR119CNR2L3MBTL1KMT2ADRD2 | |
| SCHEMBL4958144 | 0.79 | GPR119 (0.46) | GPR119CNR2L3MBTL1KMT2AMEN1 | |
| SCHEMBL4754464 | 0.78 | KDM4E (0.67) | GPR119L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL16695272 | 0.78 | CNR2 (0.73) | GPR119CNR2KMT2ADRD2PANK3 | |
| SCHEMBL972745 | 0.77 | CNR2 (0.54) | GPR119CNR2KMT2ADRD2PANK3 | |
| SCHEMBL6125262 | 0.77 | KMT2A (0.58) | GPR119CNR2KMT2ADRD2PANK3 | |
| SCHEMBL4958147 | 0.77 | GPR119 (0.44) | GPR119CNR2L3MBTL1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | disclosed |