Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | F13A1 | P00488 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | TGM1 | P22735 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941442 | 0.87 | GAA (0.68) | KDM4EL3MBTL1GAAPKMCXCR3 | |
| SCHEMBL5335588 | 0.83 | L3MBTL1 (0.91) | KDM4EL3MBTL1GAAPKMGPR119 | |
| SCHEMBL2155799 | 0.82 | KDM4E (0.74) | KDM4EL3MBTL1GAAPKMCXCR3 | |
| SCHEMBL3600596 | 0.80 | KDM4E (1.00) | KDM4EL3MBTL1GAAPKMCXCR3 | |
| SCHEMBL6809004 | 0.80 | GAA (0.60) | KDM4EL3MBTL1GAAPKMCXCR3 | |
| SCHEMBL942135 | 0.79 | CXCR3 (0.60) | KDM4EL3MBTL1GAAPKMCXCR3 | |
| SCHEMBL23207522 | 0.79 | KDM4E (0.62) | KDM4EL3MBTL1GAAPKMMAPT | |
| SCHEMBL8082196 | 0.78 | SMN1; SMN2 (0.62) | KDM4EL3MBTL1GAAMAPTSMN1; SMN2 | |
| SCHEMBL4754484 | 0.78 | GPR119 (0.54) | KDM4EL3MBTL1GAAGPR119SMN1; SMN2 | |
| SCHEMBL30582921 | 0.78 | KDM4E (0.60) | KDM4EL3MBTL1GAAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147763-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2008-12-04 | — | — | WO | disclosed |