Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 7/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754491 | 0.91 | PPARG (0.36) | PPARGPPARDPPARA | |
| SCHEMBL4754503 | 0.89 | PPARG (0.41) | PPARGPPARDPPARAACHEBACE1 | |
| SCHEMBL4754514 | 0.83 | PPARG (0.36) | PPARGPPARDPPARACTSAACHE | |
| SCHEMBL2466955 | 0.74 | PPARG (0.46) | PPARGPPARDPPARACTSACNR1 | |
| SCHEMBL4754493 | 0.73 | PPARG (0.35) | PPARGPPARDPPARA | |
| SCHEMBL4754147 | 0.72 | PPARG (0.41) | PPARGPPARDPPARAACHEBACE1 | |
| SCHEMBL2466096 | 0.68 | PPARG (0.41) | PPARGPPARDPPARAANO1ANO2 | |
| SCHEMBL2463943 | 0.66 | PPARG (0.48) | PPARGPPARDPPARAACHEBACE1 | |
| SCHEMBL4327841 | 0.64 | ERN1 (0.36) | PPARGPPARDPPARAHSP90AA1 | |
| SCHEMBL2463427 | 0.63 | PPARG (0.46) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |