Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754493 | 0.94 | PPARG (0.35) | PPARGPPARDPPARAHSD17B10MAPT | |
| SCHEMBL4754569 | 0.89 | PPARG (0.40) | PPARGPPARDPPARAHSD17B10MAPT | |
| SCHEMBL4754514 | 0.89 | PPARG (0.36) | PPARGPPARDPPARAHSD17B10TSHR | |
| SCHEMBL4754503 | 0.82 | PPARG (0.41) | PPARGPPARDPPARAHSD17B10MAPT | |
| SCHEMBL4755267 | 0.78 | PPARG (0.42) | PPARGPPARDPPARAHSD17B10MAPT | |
| SCHEMBL4754491 | 0.76 | PPARG (0.36) | PPARGPPARDPPARAMAPTNPC1 | |
| SCHEMBL2463943 | 0.76 | PPARG (0.48) | PPARGPPARDPPARAHSD17B10MAPT | |
| SCHEMBL2460888 | 0.74 | PPARG (0.52) | PPARGPPARDPPARAHSD17B10MAPT | |
| SCHEMBL4754502 | 0.72 | PPARG (0.36) | PPARGPPARDPPARACNR1ACHE | |
| SCHEMBL2466991 | 0.70 | PPARG (0.44) | PPARGPPARDPPARAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |