Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754147 | 0.94 | PPARG (0.41) | PPARGPPARDPPARAMAPTMEN1 | |
| SCHEMBL4754514 | 0.91 | PPARG (0.36) | PPARGPPARDPPARAALDH1A1S1PR1 | |
| SCHEMBL4754569 | 0.82 | PPARG (0.40) | PPARGPPARDPPARAMAPTMEN1 | |
| SCHEMBL4754491 | 0.81 | PPARG (0.36) | PPARGPPARDPPARAMAPTMEN1 | |
| SCHEMBL4754503 | 0.76 | PPARG (0.41) | PPARGPPARDPPARAMAPTMEN1 | |
| SCHEMBL4754502 | 0.73 | PPARG (0.36) | PPARGPPARDPPARA | |
| SCHEMBL2463427 | 0.73 | PPARG (0.46) | PPARGPPARDPPARAMAPTMEN1 | |
| SCHEMBL4755267 | 0.72 | PPARG (0.42) | PPARGPPARDPPARAMAPTTP53 | |
| SCHEMBL4327841 | 0.69 | ERN1 (0.36) | PPARGPPARDPPARAMAPTMEN1 | |
| SCHEMBL2463943 | 0.69 | PPARG (0.48) | PPARGPPARDPPARAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |