Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968225 | 0.90 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL968224 | 0.90 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL2845457 | 0.89 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL5504188 | 0.89 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL1862363 | 0.87 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL1862367 | 0.87 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL27758804 | 0.87 | REN (0.58) | RENCYP3A4 | |
| SCHEMBL27758803 | 0.87 | REN (0.58) | RENCYP3A4 | |
| SCHEMBL5505403 | 0.85 | REN (0.66) | RENCYP3A4 | |
| SCHEMBL8267636 | 0.84 | REN (0.61) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156832-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-1807078-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006042150-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |