Phthalic Anhydride

Phthalic Anhydride

SCHEMBL4754642

N=Nc1cccc(N)c1.O=C1OC(=O)c2ccccc21

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
ALOX15 P16050 1/20 0.47
TYMS P04818 2/20 0.40
NOS1 P29475 1/20 0.40
NPC1 O15118 4/20 0.38
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPK1 P28482 2/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
PTPRC P08575 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
APAF1 O14727 1/20 0.37
TDP2 O95551 1/20 0.37
NSD2 O96028 1/20 0.37
LMNA P02545 1/20 0.37
PLA2G1B P04054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28057114 0.82
SCHEMBL8940394 0.74 ALOX15 (0.46) TDP1ALOX15TYMSALDH1A1
Phthalic Anhydride SCHEMBL28204302 0.73 TDP1 (0.70) TDP1ALOX15TYMSNPC1RAB9A
Phthalic Anhydride SCHEMBL18917651 0.71 TDP1 (0.74) TDP1ALOX15TYMSNPC1RAB9A
Phthalic Anhydride SCHEMBL8429390 0.71 MAOB (0.61) TDP1ALOX15NPC1RAB9ASMN1; SMN2
Phthalic Anhydride SCHEMBL4436162 0.70 PBRM1 (0.56) TDP1ALOX15TYMSTSHRPTPRC
Phthalic Anhydride SCHEMBL28135943 0.69 TDP1 (0.88) TDP1ALOX15TYMSNPC1RAB9A
Phthalic Anhydride SCHEMBL29356227 0.68 TDP1 (1.00) TDP1ALOX15TYMSNPC1RAB9A
Phthalic Anhydride SCHEMBL380499 0.68 TDP1 (1.00) TDP1ALOX15TYMSNPC1RAB9A
Phthalic Anhydride SCHEMBL220 0.68 TDP1 (1.00) TDP1ALOX15TYMSNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008150643-A1 METHOD OF SEPARATING A POLYMER FROM A SOLVENT SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-12-11 WO disclosed
US-20070225479-A1 METHOD OF SEPARATING A POLYMER FROM A SOLVENT GENERAL ELECTRIC COMPANY (US) 2007-09-27 US disclosed
US-4910288-A Process for the preparation of polyetherimides GENERAL ELECTRIC COMPANY (US) 1990-03-20 US disclosed