Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754542 | 0.83 | HCAR2 (0.45) | HCAR2ATMALDH1A1BCAT2CYP2C9 | |
| SCHEMBL30267575 | 0.77 | HCAR2 (0.56) | HCAR2ATMALDH1A1BCAT2CYP2C9 | |
| SCHEMBL2491694 | 0.73 | ALDH1A1 (0.59) | HCAR2ATMALDH1A1 | |
| SCHEMBL1478348 | 0.73 | HCAR2 (0.52) | HCAR2ATMALDH1A1BCAT2CYP2C9 | |
| SCHEMBL27698129 | 0.73 | HCAR2 (0.52) | HCAR2ATMALDH1A1BCAT2CYP2C9 | |
| Hydrochloric Acid SCHEMBL30054224 | 0.71 | ALDH1A1 (0.57) | HCAR2ATMALDH1A1 | |
| SCHEMBL28108154 | 0.70 | — | — | |
| SCHEMBL1315543 | 0.68 | LMNA (0.58) | ALDH1A1 | |
| SCHEMBL13531221 | 0.68 | HCAR2 (0.42) | HCAR2ALDH1A1CYP2C9CYP2C19ABL1 | |
| SCHEMBL13531256 | 0.68 | CA12 (0.52) | HCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059519-A2 | A PROCESS FOR THE PREPARATION OF INTERMEDIATES OF ROSUVASTATIN | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-05-22 | — | — | WO | disclosed |