Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756920 | 0.86 | KDM4E (0.42) | HPGDPOLBHTTCA12CA1 | |
| SCHEMBL4757661 | 0.85 | MEN1 (0.51) | HPGDMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL4757867 | 0.85 | MEN1 (0.48) | HPGDMAPK1HTTCA12CA1 | |
| SCHEMBL4756900 | 0.79 | HPGD (0.47) | HPGDPOLBMAPK1HTTPTGS2 | |
| SCHEMBL3308517 | 0.77 | ALDH1A1 (0.44) | HPGDPOLBPTGS2CA12CA1 | |
| SCHEMBL4755662 | 0.77 | SRC (0.37) | HPGDMAPK1HTTKDM4EMEN1 | |
| SCHEMBL2560642 | 0.74 | HPGD (0.56) | HPGDPOLBHTTMEN1KMT2A | |
| SCHEMBL4790131 | 0.74 | DNM1 (0.43) | HPGDPTGS2KDM4EMEN1KMT2A | |
| SCHEMBL17748297 | 0.73 | MAPK1 (0.58) | HPGDPOLBMAPK1HTTCA12 | |
| SCHEMBL1984171 | 0.72 | HMGB1 (0.55) | HPGDMAPK1PTGS2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879661-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | claimed |
| WO-2006119821-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | claimed |