Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 15/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637958 | 0.95 | EPHX2 (0.43) | UTS2RFAAHHRH4HRH3SMN1; SMN2 | |
| SCHEMBL2230625 | 0.92 | UTS2R (0.40) | UTS2RSMN1; SMN2LMNAHTT | |
| SCHEMBL4757551 | 0.89 | UTS2R (0.38) | UTS2RFAAHHRH4HRH3SMN1; SMN2 | |
| SCHEMBL6684836 | 0.88 | SMN1; SMN2 (0.48) | UTS2RFAAHHRH4HRH3SMN1; SMN2 | |
| SCHEMBL5982655 | 0.87 | CCKBR (0.48) | UTS2RHTT | |
| SCHEMBL351149 | 0.86 | UTS2R (0.43) | UTS2RHRH4HRH3SMN1; SMN2LMNA | |
| SCHEMBL638122 | 0.85 | UTS2R (0.39) | UTS2RFAAHHRH4HRH3SMN1; SMN2 | |
| SCHEMBL5983831 | 0.84 | MEN1 (0.39) | UTS2RFAAHHRH4HRH3SMN1; SMN2 | |
| SCHEMBL638835 | 0.84 | EPHX2 (0.41) | UTS2RFAAHHRH4HRH3SMN1; SMN2 | |
| SCHEMBL2231578 | 0.83 | UTS2R (0.39) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157408-A2 | USE OF PRODRUGS OF GABA ANALOGS, ANTISPASTICITY AGENTS, AND PRODRUGS OF GABA B RECEPTOR AGONISTS FOR TREATING SPASTICITY | XENOPORT, INC. (US) | 2008-12-24 | — | — | WO | disclosed |