Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium SCHEMBL4755118 | 0.98 | TRPV1 (0.36) | TRPV1CALCRLSIGMAR1KDM4ELMNA | |
| Lithium Ion SCHEMBL4755102 | 0.90 | TRPV1 (0.35) | TRPV1CALCRLSIGMAR1KDM4ELMNA | |
| SCHEMBL4757807 | 0.81 | GRM1 (0.44) | TRPV1ENPP2 | |
| SCHEMBL13985178 | 0.80 | GRM1 (0.45) | TRPV1ENPP2 | |
| SCHEMBL13985273 | 0.76 | CALCRL (0.63) | CALCRL | |
| SCHEMBL13985041 | 0.75 | CALCRL (0.74) | CALCRL | |
| SCHEMBL4758257 | 0.73 | RXRA (0.43) | CALCRLLMNAMAPT | |
| SCHEMBL4757886 | 0.73 | NOTUM (0.48) | CALCRLLMNAMAPT | |
| Lithium Ion SCHEMBL4757812 | 0.71 | GRM1 (0.42) | ENPP2 | |
| Lithium SCHEMBL4757890 | 0.71 | NOTUM (0.48) | CALCRLLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |