Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562108 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL27960533 | 0.82 | HCAR2 (0.41) | ALDH1A1LMNAGAAHCAR2SMN1; SMN2 | |
| SCHEMBL6028711 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL3908512 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL1333841 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL13718845 | 0.81 | MGAM (0.44) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL15150014 | 0.79 | SOAT1 (0.42) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL9770041 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL7152933 | 0.79 | ALOX15 (0.48) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL27310429 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HSD17B10LMNAALOX15MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693461-A | Novel synthetic method of 4, 6-dichloro-5-methoxypyrimidine | 江苏中渊化学品有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2006011647-A1 | POLYMERIZABLE COMPOSITION, OPTICALLY ANISOTROPIC LAYER AND METHOD FOR MANUFACTURING THEREOF, OPTICAL COMPENSATORY ELEMENT, LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTAL PROJECTOR | FUJIFILM CORPORATION (JP) | 2006-02-02 | — | — | WO | disclosed |
| CN-1016778-B | spiro-substituted glutaric acid monoamides | PFIZER LTD (GB) | 1992-05-27 | — | — | CN | disclosed |
| CN-87107371-A | The glutaramide diuretic agents of spiral shell-replacement | — | 1988-07-06 | — | — | CN | disclosed |