Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222159 | 0.92 | USP2 (0.56) | SPHK2MAPTKDM4EKDM1AMAOA | |
| SCHEMBL12894562 | 0.90 | FAAH (0.61) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL1222525 | 0.88 | EGFR (0.54) | SPHK2MAPTKDM4ENR4A1NR4A2 | |
| SCHEMBL1223199 | 0.86 | MEN1 (0.53) | MAPTKDM4EKDM1AMAOAMAOB | |
| SCHEMBL12206662 | 0.85 | MAPT (0.61) | MAPTKDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL12231798 | 0.84 | MAPT (0.60) | SPHK2MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL1222175 | 0.83 | KMT2A (0.51) | MAPTKDM4EKDM1AMAOAMAOB | |
| SCHEMBL22358296 | 0.83 | KMT2A (0.68) | KDM4ERAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL1221774 | 0.83 | SCD (0.58) | RAB9ANPC1SLC6A7 | |
| SCHEMBL1221291 | 0.82 | KMT2A (0.56) | MAPTKDM4EKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | claimed |
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |