Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PREP | P48147 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1442608 | 0.89 | RAB9A (0.70) | KMT2ARAB9ASMN1; SMN2PREPDPP4 | |
| SCHEMBL20924642 | 0.88 | KMT2A (0.65) | KMT2ARAB9ASMN1; SMN2PREPDPP4 | |
| SCHEMBL4753506 | 0.88 | KMT2A (0.58) | KMT2ARAB9ASMN1; SMN2KDM4EP2RY12 | |
| SCHEMBL3275319 | 0.87 | RAB9A (0.68) | KMT2ARAB9ASMN1; SMN2PREPDPP4 | |
| SCHEMBL14335466 | 0.84 | SMN1; SMN2 (0.63) | KMT2ARAB9ASMN1; SMN2KDM4EHTT | |
| SCHEMBL22122851 | 0.84 | SMN1; SMN2 (0.63) | KMT2ARAB9ASMN1; SMN2PREPDPP4 | |
| SCHEMBL3861151 | 0.84 | KMT2A (0.61) | KMT2ARAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL20924617 | 0.83 | SMN1; SMN2 (0.61) | KMT2ARAB9ASMN1; SMN2PREPDPP4 | |
| SCHEMBL4755200 | 0.83 | SPHK2 (0.53) | KMT2ARAB9ASMN1; SMN2KDM4EHTT | |
| SCHEMBL1222690 | 0.83 | KMT2A (0.60) | KMT2ARAB9ASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | KMT2A 2479/4885RAB9A 2129/4885SMN1; SMN2 13/4885 |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | KMT2A 2479/4885RAB9A 2129/4885SMN1; SMN2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.