Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.77 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | CA12 | O43570 | 1/20 | 0.74 |
| ▸ | CA1 | P00915 | 1/20 | 0.74 |
| ▸ | CA2 | P00918 | 1/20 | 0.74 |
| ▸ | HTR1A | P08908 | 1/20 | 0.74 |
| ▸ | CA4 | P22748 | 1/20 | 0.74 |
| ▸ | CA6 | P23280 | 1/20 | 0.74 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.74 |
| ▸ | CA5A | P35218 | 1/20 | 0.74 |
| ▸ | CA7 | P43166 | 1/20 | 0.74 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.74 |
| ▸ | CA9 | Q16790 | 1/20 | 0.74 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.74 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.74 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.66 |
| ▸ | AQP1 | P29972 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855450 | 1.00 | APP (0.77) | APPCISD1ALDH1A1CA12CA1 | |
| SCHEMBL29855566 | 0.87 | APP (1.00) | APPCISD1ALDH1A1CA12CA1 | |
| SCHEMBL12418650 | 0.87 | APP (1.00) | APPCISD1ALDH1A1CA12CA1 | |
| SCHEMBL12418656 | 0.87 | AQP1 (0.82) | APPCISD1ALDH1A1CA12CA1 | |
| SCHEMBL20369158 | 0.85 | APP (0.81) | APPCISD1ALDH1A1CA12CA1 | |
| SCHEMBL29855535 | 0.85 | APP (0.81) | APPCISD1ALDH1A1CA12CA1 | |
| SCHEMBL11929317 | 0.85 | APP (0.82) | APPCISD1ALDH1A1CA12CA1 | |
| SCHEMBL11820603 | 0.85 | APP (0.80) | APPCISD1ALDH1A1CA12CA1 | |
| SCHEMBL22852478 | 0.85 | CISD1 (0.80) | APPCISD1ALDH1A1CA12CA1 | |
| Furosemide SCHEMBL29406913 | 0.85 | CISD1 (1.00) | APPCISD1ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11774442-B2 | Molecule sensor systems | ENEVOLV, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| EP-4053146-A2 | MOLECULE SENSOR SYSTEMS | enEvolv, Inc. (US) | 2022-09-07 | — | — | EP | disclosed |
| WO-2020257940-A1 | FUROSEMIDE ANALOGUES AND COMPOSITIONS AND USES THEREOF FOR TREATMENT OF ALZHEIMER'S DISEASE | UNIVERSITY HEALTH NETWORK (CA) | 2020-12-30 | — | — | WO | disclosed |
| EP-1968603-A2 | THERAPEUTIC AMINE-ARYLSULFONAMIDE CONJUGATE COMPOUNDS | Algebra Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007079470-A2 | THERAPEUTIC AMINE-ARYLSULFONAMIDE CONJUGATE COMPOUNDS | ALGEBRA, INC. (US) | 2007-07-12 | — | — | WO | disclosed |