Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754569 | 0.84 | PPARG (0.40) | PPARGPPARAPPARDTSHRGAA | |
| SCHEMBL2465292 | 0.78 | PPARG (0.50) | PPARGPPARAPPARDTSHRGAA | |
| SCHEMBL4754147 | 0.78 | PPARG (0.41) | PPARGPPARAPPARDTSHRGAA | |
| SCHEMBL4754493 | 0.72 | PPARG (0.35) | PPARGPPARAPPARDGAAHSD17B10 | |
| SCHEMBL4031523 | 0.71 | PPARG (0.68) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL4754514 | 0.70 | PPARG (0.36) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL4754503 | 0.67 | PPARG (0.41) | PPARGPPARAPPARDTSHRGAA | |
| SCHEMBL4327847 | 0.65 | NPC1 (0.42) | PPARGPPARAPPARDTSHRGAA | |
| SCHEMBL4324890 | 0.65 | PPARG (0.50) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL14275899 | 0.64 | CYP2D6 (0.51) | NPC1RAB9ASMN1; SMN2TP53CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |