Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18525099 | 0.82 | HRH3 (0.35) | HRH3LMNACYP2D6KCNH2SMN1; SMN2 | |
| SCHEMBL18525070 | 0.78 | EPHX1 (0.42) | DPP4HRH3 | |
| SCHEMBL2745873 | 0.78 | GAA (0.51) | DPP4LMNASMN1; SMN2GAAHSD17B10 | |
| SCHEMBL5606073 | 0.78 | LMNA (0.56) | DPP4LMNASMN1; SMN2HPGDGAA | |
| SCHEMBL19502780 | 0.77 | DPP4 (0.43) | DPP4HRH3LMNACYP2D6KCNH2 | |
| SCHEMBL15841239 | 0.77 | ALDH1A1 (0.47) | DPP4LMNASMN1; SMN2HPGDGAA | |
| SCHEMBL2745757 | 0.77 | DPP4 (0.43) | DPP4LMNATLR9TLR8TLR7 | |
| SCHEMBL3764738 | 0.75 | EPHX2 (0.43) | SMN1; SMN2 | |
| SCHEMBL2746438 | 0.74 | SMN1; SMN2 (0.44) | DPP4LMNASMN1; SMN2HPGDGAA | |
| SCHEMBL2746501 | 0.74 | LMNA (0.40) | DPP4HRH3LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |