Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499635 | 0.90 | REN (0.46) | SLC6A4MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL4754002 | 0.88 | SLC6A4 (0.56) | SLC6A4KMT2ACYP1A2CYP2D6IDO1 | |
| SCHEMBL499257 | 0.80 | AOC3 (0.40) | SLC6A4MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL498922 | 0.78 | SLC6A4 (0.52) | SLC6A4MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL499203 | 0.78 | SLC6A4 (0.52) | SLC6A4MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL499694 | 0.76 | REN (0.48) | SLC6A4MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL499256 | 0.76 | REN (0.44) | SLC6A4MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL4755350 | 0.75 | SLC6A4 (0.40) | SLC6A4MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL26599219 | 0.74 | GPR139 (0.47) | MEN1KMT2AALDH1A1GPR139ATM | |
| SCHEMBL4754003 | 0.72 | SLC6A4 (0.44) | SLC6A4MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156816-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |