Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 10/20 | 0.53 |
| ▸ | PPARD | Q03181 | 6/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393180 | 0.89 | LTA4H (0.67) | LTA4HPPARGPPARDPPARAMAOB | |
| SCHEMBL7033327 | 0.88 | PPARG (0.67) | LTA4HPPARGPPARDPPARAMAOB | |
| SCHEMBL3939992 | 0.87 | LTA4H (0.59) | LTA4HPPARGPPARDPPARAMAOB | |
| SCHEMBL4758161 | 0.82 | PPARA (0.60) | LTA4HPPARGPPARDPPARA | |
| SCHEMBL3204956 | 0.81 | ATM (0.53) | MAPTL3MBTL1RAB9A | |
| SCHEMBL5689720 | 0.80 | LTA4H (0.51) | LTA4HPPARGPPARDPPARAMAOB | |
| Ammonia Solution, Strong SCHEMBL20513680 | 0.80 | ATM (0.51) | MAPTL3MBTL1RAB9A | |
| SCHEMBL3938329 | 0.79 | ESR1 (0.49) | LTA4HPPARGPPARDPPARAMAPT | |
| Methylene Chloride SCHEMBL29038775 | 0.78 | ATM (0.50) | MAPTL3MBTL1RAB9A | |
| SCHEMBL3105018 | 0.78 | LTA4H (0.52) | LTA4HPPARGMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |