SCHEMBL4758161

SCHEMBL4758161

CCOC(Cc1ccc(OCCOCc2ccccc2)cc1)C(=O)OC

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 16/20 0.60
PPARG P37231 15/20 0.60
PPARD Q03181 9/20 0.60
LTA4H P09960 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4756258 0.92 PPARA (0.61) PPARAPPARGPPARD
SCHEMBL4755486 0.90 PPARA (0.74) PPARAPPARGPPARD
SCHEMBL7191581 0.89 PPARA (0.73) PPARAPPARGPPARDLTA4H
SCHEMBL5364064 0.89 PPARA (0.73) PPARAPPARGPPARDLTA4H
SCHEMBL4756297 0.89 PPARG (0.47) PPARAPPARGPPARDLTA4H
SCHEMBL4756299 0.86 PPARA (0.63) PPARAPPARGPPARD
SCHEMBL7033327 0.84 PPARG (0.67) PPARAPPARGPPARDLTA4H
SCHEMBL28747287 0.83 PPARA (0.67) PPARAPPARGPPARDLTA4H
SCHEMBL4755481 0.82 LTA4H (0.54) PPARAPPARGPPARDLTA4H
SCHEMBL5386395 0.82 PPARA (0.69) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008010238-A2 ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS LUPIN LIMITED (IN) 2008-01-24 WO disclosed