Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.57 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14619460 | 0.90 | KCNN4 (0.47) | KCNN4KIF11KCNA3TSHRCYP19A1 | |
| SCHEMBL28060275 | 0.83 | KCNN4 (0.55) | KCNN4KIF11KCNA3TSHRCYP19A1 | |
| SCHEMBL27565399 | 0.82 | KCNN4 (0.53) | KCNN4KIF11KCNA3TSHRCYP19A1 | |
| SCHEMBL316134 | 0.78 | KIF11 (0.50) | KCNN4KIF11TSHRMAPK1CA2 | |
| Hydrochloric Acid SCHEMBL7233523 | 0.75 | KIF11 (0.48) | KCNN4KIF11TSHRMAPK1CA2 | |
| SCHEMBL17454867 | 0.74 | KIF11 (0.54) | KCNN4KIF11KCNA3TSHRCYP19A1 | |
| SCHEMBL27459558 | 0.74 | KCNN4 (0.72) | KCNN4KIF11KCNA3TSHRCYP19A1 | |
| SCHEMBL3861253 | 0.73 | KIF11 (0.36) | KCNN4KIF11CYP3A4ALOX15SMN1; SMN2 | |
| SCHEMBL4955482 | 0.73 | KCNN4 (0.45) | KCNN4KIF11KCNA3TSHRCYP19A1 | |
| SCHEMBL28772995 | 0.73 | KCNN4 (0.44) | KCNN4KIF11KCNA3TSHRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156701-A2 | HYDROXAMATE INHIBITORS OF INSULIN-DEGRADING ENZYME AND USES THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2008-12-24 | — | — | WO | disclosed |