Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 11/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25449 | 0.94 | MAPK1 (0.57) | MAPK1HPGDHCAR2NPC1POLB | |
| SCHEMBL26820 | 0.87 | HPGD (0.54) | HPGDHCAR2DAOHCAR3CYTH3 | |
| Hydrochloric Acid SCHEMBL27727584 | 0.86 | HPGD (0.52) | HPGDHCAR2DAOHCAR3CYTH3 | |
| SCHEMBL6350652 | 0.83 | HPGD (0.50) | MAPK1HPGDNPC1POLBRAB9A | |
| SCHEMBL14688254 | 0.78 | HPGD (0.46) | MAPK1HPGDNPC1POLBRAB9A | |
| SCHEMBL6722955 | 0.78 | HPGD (0.46) | MAPK1HPGDHCAR2NPC1POLB | |
| SCHEMBL3827239 | 0.78 | POLB (0.48) | HPGDNPC1POLBRAB9AKMT2A | |
| SCHEMBL15981916 | 0.76 | HPGD (0.52) | MAPK1HPGDHCAR2DAOKMT2A | |
| SCHEMBL1554374 | 0.73 | HPGD (0.45) | MAPK1HPGDHCAR2NPC1POLB | |
| SCHEMBL23534328 | 0.73 | ESR1 (0.49) | MAPK1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015271-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THE USE AS A MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-02-07 | — | — | WO | disclosed |