Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25449 | 0.83 | MAPK1 (0.57) | HPGDMAPK1NPC1MAPTKDM4E | |
| SCHEMBL14688254 | 0.79 | HPGD (0.46) | HPGDMAPK1ALDH1A1LMNANPC1 | |
| SCHEMBL3827239 | 0.79 | POLB (0.48) | HPGDNPC1MAPTTP53NPSR1 | |
| SCHEMBL4755850 | 0.78 | MAPK1 (0.51) | HPGDMAPK1NPC1L3MBTL1HCAR3 | |
| SCHEMBL15981916 | 0.77 | HPGD (0.52) | HPGDMAPK1ALDH1A1LMNAMAPT | |
| SCHEMBL6350652 | 0.76 | HPGD (0.50) | HPGDMAPK1LMNANPC1MAPT | |
| SCHEMBL25186196 | 0.76 | MAPK1 (0.61) | MAPK1ALDH1A1LMNANPC1MAPT | |
| SCHEMBL166665 | 0.76 | MAPK1 (0.43) | HPGDMAPK1ALDH1A1LMNANPC1 | |
| SCHEMBL972735 | 0.75 | HPGD (0.43) | HPGDMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL26820 | 0.75 | HPGD (0.54) | HPGDHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157892-A1 | Pesticidal fluoroethyl pyrazoles | CROMPTON CO./CIE | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157892-A1 | Pesticidal fluoroethyl pyrazoles | CBR3, AADAC, HDHD5 | HPGD 530/4885CRHBP 1391/4885CRHR2 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.