SCHEMBL26820

SCHEMBL26820

O=C(O)c1cc([N+](=O)[O-])[nH]n1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.54
HCAR2 Q8TDS4 15/20 0.50
DAO P14920 1/20 0.50
HCAR3 P49019 3/20 0.46
CYTH3 O43739 1/20 0.46
BTK Q06187 1/20 0.46
EPN1 Q9Y6I3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27727584 0.98 HPGD (0.52) HPGDHCAR2DAOHCAR3CYTH3
SCHEMBL4755850 0.87 MAPK1 (0.51) HPGDHCAR2DAOHCAR3CYTH3
SCHEMBL5969919 0.83 HPGD (0.52) HPGDHCAR2DAOCYTH3BTK
SCHEMBL15981916 0.83 HPGD (0.52) HPGDHCAR2DAOHCAR3
SCHEMBL5013388 0.83 HPGD (0.52) HPGDHCAR2DAOCYTH3BTK
SCHEMBL42514 0.83 HPGD (0.52) HPGDHCAR2DAO
SCHEMBL17928435 0.83 HPGD (0.49) HPGDHCAR2DAOHCAR3CYTH3
SCHEMBL18680106 0.79 HPGD (0.49) HPGDHCAR2DAOHCAR3
SCHEMBL25449 0.79 MAPK1 (0.57) HPGDHCAR2
SCHEMBL6305513 0.79 HPGD (0.49) HPGDHCAR2DAOHCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119638705-A Energetic compound taking polyaminotriazole as framework, energetic ionic salt and preparation method thereof 南京理工大学 2025-03-18 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
EP-1670787-A4 CYTOKINE INHIBITORS KEMIA INC (US) 2009-04-22 EP claimed
CN-1878769-A Cytokine inhibitors KEMIA INC (US) 2006-12-13 CN claimed
EP-1670787-A2 CYTOKINE INHIBITORS Kemia, INC. (US) 2006-06-21 EP claimed
US-7005439-B2 Compounds ASTRAZENECA AB (SE) 2006-02-28 US claimed
US-20050107399-A1 Cytokine inhibitors KEMIA, INC. 2005-05-19 US claimed
WO-2005023761-A2 CYTOKINE INHIBITORS KEMIA, INC. (US) 2005-03-17 WO claimed
EP-1299356-B1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2004-02-11 EP claimed
CN-1447794-A Novel compounds ASTRAZENECA AB (SE) 2003-10-08 CN claimed
EP-1299356-A1 NOVEL COMPOUNDS AstraZeneca AB (SE) 2003-04-09 EP claimed
WO-2001098272-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2001-12-27 WO claimed
US-12577266-B2 Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens VENTANA MEDICAL SYSTEMS, INC. (US) 2026-03-17 US disclosed
WO-1998054702-A1 MAGNETIC RECORDING MEDIA INCORPORATING SURFACE TREATED MAGNETIC PIGMENT IMATION CORP. (US) 1998-12-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS HPGD 3676/4885HCAR2 4789/4885DAO 895/4885
US-20050107399-A1 Cytokine inhibitors TNF, IL1RN, IL1A HPGD 518/4885HCAR2 281/4885DAO 1926/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS HPGD 3676/4885HCAR2 4789/4885DAO 895/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS HPGD 3676/4885HCAR2 4789/4885DAO 895/4885
US-12577266-B2 Protein proximity assay in formalin fixed paraffin embedded tissue using caged haptens ACP1, AOX1, PTMS HPGD 1327/4885HCAR2 3840/4885DAO 852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.