Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295739 | 0.90 | HTT (0.56) | L3MBTL1SIRT2ALDH1A1HPGDRAB9A | |
| SCHEMBL4297348 | 0.88 | SIRT2 (0.49) | L3MBTL1PKMSIRT2ALDH1A1HPGD | |
| SCHEMBL4296812 | 0.87 | SIRT2 (0.48) | L3MBTL1PKMSIRT2ALDH1A1HPGD | |
| Lithium Ion SCHEMBL4296808 | 0.85 | SIRT2 (0.46) | L3MBTL1SIRT2ALDH1A1HPGDRAB9A | |
| SCHEMBL4295736 | 0.85 | SIRT2 (0.43) | L3MBTL1SIRT2KIF11 | |
| SCHEMBL4756161 | 0.78 | MAPK8 (0.44) | SIRT2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4771680 | 0.77 | KDM4E (0.71) | L3MBTL1PKMALDH1A1HPGDRAB9A | |
| SCHEMBL4293392 | 0.77 | SIRT2 (0.47) | SIRT2KDM4EKIF11 | |
| SCHEMBL4292881 | 0.76 | SIRT2 (0.42) | SIRT2ALDH1A1HPGDRAB9AKDM4E | |
| SCHEMBL4288771 | 0.76 | SIRT2 (0.46) | SIRT2KDM4EKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896048-A2 | PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE (PACAP) RECEPTOR (VPAC2) AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE | Bayer Pharmaceuticals Corporation (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006121588-A2 | PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE (PACAP) RECEPTOR (VPAC2) AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-11-16 | — | — | WO | disclosed |