Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366021 | 1.00 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6911104 | 1.00 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27708782 | 0.84 | ENPEP (0.41) | CYP1A2GABRR1MMP1MMP2MMP3 | |
| SCHEMBL17792657 | 0.84 | GAA (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL13643227 | 0.84 | GAA (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1245716 | 0.84 | GAA (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5986156 | 0.84 | MMP1 (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL30422146 | 0.83 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL29124713 | 0.83 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4548423 | 0.83 | HCAR2 (0.39) | ALDH1A1CYP1A2LMNAGABRR1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |