Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 20/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209260 | 0.91 | AURKA (0.66) | AURKAKCNH2FLT3 | |
| SCHEMBL13985590 | 0.90 | AURKA (0.76) | AURKAKCNH2FLT3 | |
| SCHEMBL13985667 | 0.88 | AURKA (0.64) | AURKAKCNH2FLT3 | |
| SCHEMBL4757123 | 0.88 | AURKA (0.60) | AURKAKCNH2FLT3 | |
| SCHEMBL13985594 | 0.83 | AURKA (0.55) | AURKAKCNH2FLT3 | |
| SCHEMBL208679 | 0.82 | AURKA (0.77) | AURKAKCNH2FLT3 | |
| SCHEMBL4757490 | 0.80 | AURKA (0.50) | AURKAKCNH2 | |
| SCHEMBL13985719 | 0.80 | AURKA (0.58) | AURKAKCNH2FLT3 | |
| SCHEMBL13985474 | 0.80 | AURKA (0.52) | AURKAKCNH2 | |
| SCHEMBL13985734 | 0.80 | AURKA (0.77) | AURKAKCNH2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | claimed |
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |