Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757259 | 0.89 | REN (0.36) | REN | |
| SCHEMBL4756432 | 0.86 | — | — | |
| SCHEMBL4757263 | 0.86 | REN (0.33) | REN | |
| SCHEMBL4754056 | 0.86 | REN (0.42) | REN | |
| SCHEMBL4754629 | 0.78 | — | — | |
| SCHEMBL3466069 | 0.75 | PDE2A (0.32) | REN | |
| SCHEMBL3464389 | 0.75 | PDE2A (0.32) | REN | |
| SCHEMBL4754600 | 0.74 | BACE1 (0.35) | — | |
| SCHEMBL4756435 | 0.72 | REN (0.41) | REN | |
| SCHEMBL4756428 | 0.72 | REN (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911762-A1 | Amino alcohols and their use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |