Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757259 | 0.90 | REN (0.36) | REN | |
| SCHEMBL4756439 | 0.86 | REN (0.33) | REN | |
| SCHEMBL4754056 | 0.86 | REN (0.42) | REN | |
| SCHEMBL4754633 | 0.80 | CTSD (0.33) | RENCTSDF10PRSS1ALDH1A1 | |
| SCHEMBL4754095 | 0.79 | REN (0.30) | REN | |
| SCHEMBL4756814 | 0.79 | GSK3B (0.33) | RENCTSDF10PRSS1ALDH1A1 | |
| SCHEMBL4754600 | 0.78 | BACE1 (0.35) | — | |
| SCHEMBL4755841 | 0.77 | — | — | |
| SCHEMBL3466069 | 0.73 | PDE2A (0.32) | REN | |
| SCHEMBL3464389 | 0.73 | PDE2A (0.32) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911762-A1 | Amino alcohols and their use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |