Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 6/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23295733 | 0.77 | ELANE (0.39) | ELANEPARP1CYP1A2ACHE | |
| SCHEMBL4754611 | 0.71 | TSHR (0.33) | TSHRELANEPARP1PDE10ACYP1A2 | |
| SCHEMBL6180444 | 0.71 | ALDH1A1 (0.44) | USP8TSHRELANE | |
| SCHEMBL4755945 | 0.70 | ELANE (0.35) | ELANEPARP1 | |
| SCHEMBL4757324 | 0.68 | ELANE (0.33) | ELANEPARP1ACHE | |
| SCHEMBL3673625 | 0.63 | MAPK1 (0.47) | USP8TSHRCYP1A2 | |
| SCHEMBL30201734 | 0.63 | MAPK1 (0.47) | USP8TSHRCYP1A2 | |
| SCHEMBL21609975 | 0.62 | TSHR (0.38) | USP8TSHRELANEPDE10ACYP1A2 | |
| SCHEMBL27359621 | 0.62 | PDE10A (0.37) | TSHRELANEPARP1PDE10ACYP1A2 | |
| SCHEMBL11627568 | 0.61 | ELANE (0.45) | TSHRELANEPARP1CYP1A2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154905-A2 | MODIFICATIONS OF THE HISTONE DEACETYLASE INHIBITOR SUBEROYLANILIDE HYDROXAMIC ACID | SCHEBO BIOTECH AG (DE) | 2008-12-24 | — | — | WO | disclosed |