Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574962 | 1.00 | SLC8A1 (0.33) | SLC8A1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL4574970 | 1.00 | SLC8A1 (0.33) | SLC8A1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL4756646 | 0.87 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL4962494 | 0.85 | KMT2A (0.37) | SLC8A1ALDH1A1 | |
| SCHEMBL4964547 | 0.85 | HTT (0.38) | SLC8A1 | |
| SCHEMBL4574531 | 0.83 | SLC8A1 (0.40) | SLC8A1RAB9A | |
| SCHEMBL2689406 | 0.82 | SLC8A1 (0.32) | SLC8A1ALDH1A1 | |
| SCHEMBL4965120 | 0.82 | BRD4 (0.35) | SLC8A1 | |
| SCHEMBL4590893 | 0.82 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL4574802 | 0.81 | RORC (0.38) | SLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095912-A2 | ENANTIOPURE PHARMACOLOGICALLY ACTIVE TRICYCLIC BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |