Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2842712 | 0.87 | BCL2 (0.41) | CTSSCTSKHTR7KAT6AKIF11 | |
| SCHEMBL7773926 | 0.77 | HTR7 (0.41) | CTSSCTSKHTR7KAT6AHTR1A | |
| SCHEMBL12881753 | 0.76 | HTR7 (0.53) | CTSSCTSKHTR7KAT6AFFAR1 | |
| SCHEMBL196298 | 0.75 | CTSS (0.51) | CTSSCTSKHTR7KIF11 | |
| SCHEMBL30777855 | 0.75 | CTSS (0.51) | CTSSCTSKHTR7KIF11 | |
| SCHEMBL1865690 | 0.75 | CSNK1E (0.43) | — | |
| SCHEMBL4302188 | 0.74 | TAAR1 (0.42) | TAAR1 | |
| SCHEMBL3571311 | 0.74 | BRD4 (0.49) | KAT6AFFAR1 | |
| SCHEMBL4746482 | 0.74 | CTSS (0.39) | CTSSCTSKHTR7SLC5A1HTR1A | |
| SCHEMBL24005570 | 0.73 | CTSS (0.50) | CTSSCTSKHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |