Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758988 | 0.79 | HCAR2 (0.44) | LMNAHCAR2KMT2AALDH1A1HPGD | |
| SCHEMBL4756679 | 0.75 | HSD17B10 (0.45) | LMNAHCAR2KDM4EKMT2AALDH1A1 | |
| SCHEMBL4756681 | 0.75 | HSD17B10 (0.45) | LMNAHCAR2KDM4EKMT2AALDH1A1 | |
| SCHEMBL12635150 | 0.74 | KMT2A (0.66) | LMNATSHRKMT2AHTR1AADRA2A | |
| SCHEMBL31108006 | 0.74 | KMT2A (0.66) | LMNATSHRKMT2AHTR1AADRA2A | |
| SCHEMBL4093439 | 0.70 | HTR1A (0.47) | LMNATSHRLY96KMT2AHTR1A | |
| SCHEMBL8037990 | 0.70 | LMNA (0.52) | LMNATSHRKMT2AHTR1AADRA2A | |
| SCHEMBL17204784 | 0.70 | KMT2A (0.55) | LMNAHCAR2KDM4EKMT2AALDH1A1 | |
| SCHEMBL14783602 | 0.69 | LMNA (0.51) | LMNATSHRKDM4EKMT2AHTR1A | |
| SCHEMBL17386433 | 0.69 | HTR1A (0.46) | LMNATSHRLY96KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073534-A1 | METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-06-19 | — | — | WO | disclosed |