SCHEMBL4756864

SCHEMBL4756864

CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)C(C)C)C(=O)NC(Cc1c[nH]cn1)C(=O)N1CCCC1CC(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.79

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LNPEP Q9UIQ6 9/20 0.79
ANPEP P15144 5/20 0.79
NTSR2 O95665 2/20 0.58
NTSR1 P30989 2/20 0.58
AGTR1 P30556 1/20 0.50
AGTR2 P50052 1/20 0.50
F2 P00734 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Angiotensin Iv SCHEMBL4322236 0.90 LNPEP (0.68) LNPEPANPEPNTSR2NTSR1AGTR1
Angiotensin Iv SCHEMBL4322224 0.90 LNPEP (0.68) LNPEPANPEPNTSR2NTSR1AGTR1
SCHEMBL4757569 0.89 LNPEP (0.63) LNPEPANPEPNTSR2NTSR1AGTR1
SCHEMBL4756901 0.87 LNPEP (0.61) LNPEPANPEPNTSR2NTSR1AGTR1
SCHEMBL9010597 0.87 LNPEP (0.64) LNPEPANPEPNTSR2NTSR1AGTR1
SCHEMBL9010601 0.87 LNPEP (0.64) LNPEPANPEPNTSR2NTSR1AGTR1
SCHEMBL29602804 0.87 LNPEP (0.59) LNPEPANPEPNTSR2NTSR1AGTR1
SCHEMBL4757539 0.86 LNPEP (0.60) LNPEPANPEPAGTR1AGTR2F2
SCHEMBL13081986 0.85 LNPEP (0.60) LNPEPANPEPNTSR2NTSR1AGTR1
SCHEMBL11204440 0.85 LNPEP (0.60) LNPEPANPEPNTSR2NTSR1AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120115163-A1 MARKED PEPTIDES AND USE THEREOF FOR ASSAYING CIRCULATING IRAP VRIJE UNIVERSITEIT BRUSSEL (BE) 2012-05-10 US disclosed
WO-2010133806-A2 MARKED PEPTIDES AND USE THEREOF FOR ASSAYING CIRCULATING IRAP UNIVERSITE JOSEPH FOURIER (FR) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115163-A1 MARKED PEPTIDES AND USE THEREOF FOR ASSAYING CIRCULATING IRAP IAPP, ANPEP, ENPEP LNPEP 12/4885ANPEP 2/4885NTSR2 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.