Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755037 | 0.92 | CA12 (0.42) | SLC6A2SLC6A4SLC6A3CA12CA1 | |
| SCHEMBL231497 | 0.81 | MAPT (0.48) | — | |
| SCHEMBL31385899 | 0.80 | CA12 (0.49) | HTR3ACA12CA1CA2CA7 | |
| SCHEMBL31386022 | 0.80 | CA12 (0.49) | HTR3ACA12CA1CA2CA7 | |
| SCHEMBL13985025 | 0.80 | HTR3A (0.50) | HTR3A | |
| SCHEMBL4755119 | 0.79 | PDE4A (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18617801 | 0.76 | HTR3A (0.51) | SLC6A2SLC6A4SLC6A3HTR3A | |
| Oxalic Acid SCHEMBL829222 | 0.75 | HTR3A (0.54) | HTR3A | |
| SCHEMBL7589274 | 0.74 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2662880 | 0.74 | CA12 (0.62) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |