Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MPC2 | O95563 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281156 | 0.79 | PPARG (0.67) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL4756809 | 0.78 | ALOX5 (0.58) | MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4756816 | 0.78 | ALOX5 (0.58) | MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL12060194 | 0.78 | PPARG (0.66) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL18388427 | 0.77 | PPARG (0.65) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL11925107 | 0.76 | PPARG (0.64) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL10281135 | 0.76 | PPARG (0.64) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL13743064 | 0.76 | PPARG (0.69) | PPARGCYP3A4RXRAL3MBTL1MAPT | |
| SCHEMBL26328531 | 0.76 | PPARG (0.69) | PPARGCYP3A4RXRAL3MBTL1MAPT | |
| SCHEMBL4757129 | 0.75 | PPARG (0.62) | PPARGCYP3A4RXRAMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075380-A2 | PROCESS FOR THE PREPARATION OF THIAZOLIDINE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-06-26 | — | — | WO | disclosed |