Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | KDM1A | O60341 | 9/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725262 | 0.82 | CYP19A1 (0.44) | CYP19A1KDM1AHSP90AB1 | |
| SCHEMBL4725266 | 0.79 | CYP19A1 (0.45) | CYP19A1KDM1AHSP90AB1 | |
| SCHEMBL7703700 | 0.78 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL475487 | 0.78 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL3191348 | 0.78 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL1448111 | 0.78 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL3854950 | 0.78 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL18093988 | 0.78 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL21273903 | 0.78 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL475486 | 0.78 | ABCB1 (0.52) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1892042-A1 | Proline derivatives supported on polymers through triazole or tetrazole linkers for organocatalytic applications | Institut Catala D'Investigacio Quimica (ES) | 2008-02-27 | — | — | EP | disclosed |