Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725262 | 0.94 | CYP19A1 (0.44) | CYP19A1KDM1AHSP90AB1ALDH1A1LMNA | |
| SCHEMBL16990199 | 0.84 | TSHR (0.51) | ALDH1A1ECE1 | |
| SCHEMBL4757224 | 0.79 | CYP19A1 (0.44) | CYP19A1KDM1AHSP90AB1 | |
| SCHEMBL6017192 | 0.77 | TSHR (0.52) | ALDH1A1LMNAECE1 | |
| SCHEMBL6936885 | 0.74 | AGTR2 (0.46) | — | |
| SCHEMBL12849519 | 0.74 | AGTR2 (0.46) | — | |
| SCHEMBL6515997 | 0.72 | AGTR2 (0.56) | — | |
| SCHEMBL15241314 | 0.72 | AGTR2 (0.56) | — | |
| SCHEMBL29921 | 0.72 | AGTR2 (0.56) | — | |
| SCHEMBL6281354 | 0.72 | AGTR2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022961-A1 | N-HETEROCYCLES SUPPORTED ON POLYMERS THROUGH TRIAZOLE OR TETRAZOLE LINKERS FOR ORGANOCATALYTIC APPLICATIONS | INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2008-02-28 | — | — | WO | disclosed |