SCHEMBL4725262 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CYP19A1	P11511	11/20	0.44

▸	KDM1A	O60341	2/20	0.41

▸	HSP90AB1	P08238	1/20	0.41

▸	ALDH1A1	P00352	1/20	0.40

▸	LMNA	P02545	1/20	0.40

▸	F10	P00742	1/20	0.39

▸	ECE1	P42892	1/20	0.39

▸	MGAM	O43451	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4725266	0.94	CYP19A1 (0.45)	CYP19A1KDM1AHSP90AB1ALDH1A1LMNA
SCHEMBL4757224	0.82	CYP19A1 (0.44)	CYP19A1KDM1AHSP90AB1
SCHEMBL6017192	0.82	TSHR (0.52)	ALDH1A1LMNAECE1
SCHEMBL16990199	0.78	TSHR (0.51)	ALDH1A1ECE1
SCHEMBL13758532	0.73	ALDH1A1 (0.46)	ALDH1A1LMNA
SCHEMBL8863233	0.72	POLB (0.56)	ALDH1A1LMNAECE1
SCHEMBL9544372	0.72	POLB (0.53)	ALDH1A1LMNAECE1
SCHEMBL9544370	0.72	POLB (0.53)	ALDH1A1LMNAECE1
SCHEMBL13627005	0.71	ALDH1A1 (0.46)	ALDH1A1LMNA
SCHEMBL15417732	0.71	ABCB1 (0.48)	ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008022961-A1	N-HETEROCYCLES SUPPORTED ON POLYMERS THROUGH TRIAZOLE OR TETRAZOLE LINKERS FOR ORGANOCATALYTIC APPLICATIONS	INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES)	2008-02-28	—	—	WO	disclosed