Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047596 | 0.78 | MEN1 (0.43) | MEN1POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4040561 | 0.76 | MEN1 (0.40) | MEN1POLBKMT2A | |
| SCHEMBL1996883 | 0.72 | MEN1 (0.38) | MEN1POLBKMT2A | |
| SCHEMBL9337723 | 0.72 | MEN1 (0.35) | MEN1POLBKMT2A | |
| SCHEMBL28604797 | 0.72 | ALDH1A1 (0.41) | MEN1POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL776267 | 0.72 | ALDH1A1 (0.41) | MEN1POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28225733 | 0.70 | ALDH1A1 (0.39) | MEN1POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15062781 | 0.70 | ALDH1A1 (0.39) | MEN1POLBKMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29022150 | 0.70 | ALDH1A1 (0.39) | MEN1POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9555416 | 0.70 | CTSL (0.38) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | disclosed |