Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757395 | 1.00 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL22686517 | 0.88 | ALDH1A1 (0.37) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL22686516 | 0.88 | ALDH1A1 (0.37) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL9343626 | 0.79 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL9637660 | 0.79 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL780325 | 0.79 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL7621977 | 0.78 | CA12 (0.35) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL4211542 | 0.77 | CA1 (0.46) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL495977 | 0.77 | CA1 (0.46) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL495979 | 0.77 | CA1 (0.46) | ALDH1A1USP2TSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |