Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686517 | 0.88 | ALDH1A1 (0.37) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL22686516 | 0.88 | ALDH1A1 (0.37) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL5680070 | 0.86 | ALDH1A1 (0.36) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL13316584 | 0.84 | KDM4E (0.31) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL4757395 | 0.79 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL4755958 | 0.79 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL8638824 | 0.79 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL4755954 | 0.79 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL4757396 | 0.79 | ALDH1A1 (0.42) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL5990289 | 0.78 | CA1 (0.59) | ALDH1A1USP2TSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372816-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-07-29 | — | — | EP | disclosed |
| WO-1990006304-A1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-06-14 | — | — | WO | disclosed |
| EP-0372816-A1 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-06-13 | — | — | EP | disclosed |