Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.50 |
| ▸ | PPARA | Q07869 | 12/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790590 | 1.00 | PPARG (0.50) | PPARGPPARALMNAL3MBTL1PPARD | |
| SCHEMBL6715234 | 0.91 | PPARA (0.61) | PPARGPPARALMNAL3MBTL1PPARD | |
| SCHEMBL4756245 | 0.91 | PPARA (0.61) | PPARGPPARALMNAL3MBTL1PPARD | |
| SCHEMBL4790089 | 0.90 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL4756258 | 0.84 | PPARA (0.61) | PPARGPPARALMNAL3MBTL1PPARD | |
| SCHEMBL4756241 | 0.84 | PPARA (0.46) | PPARGPPARALMNAPPARDKMT2A | |
| SCHEMBL4758162 | 0.84 | PPARA (0.46) | PPARGPPARALMNAPPARDKMT2A | |
| SCHEMBL4757538 | 0.83 | NR1H4 (0.43) | PPARGPPARALMNAPPARDKMT2A | |
| SCHEMBL6716374 | 0.81 | PPARA (0.45) | PPARGPPARALMNANR4A2RXRA | |
| SCHEMBL6716134 | 0.81 | PPARA (0.74) | PPARGPPARALMNAL3MBTL1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |