Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112304 | 1.00 | REN (0.41) | RENCYP3A4KMT2A | |
| SCHEMBL3114574 | 0.90 | REN (0.47) | RENCYP3A4 | |
| SCHEMBL3113055 | 0.90 | REN (0.47) | RENCYP3A4 | |
| SCHEMBL4757727 | 0.89 | REN (0.45) | RENCYP3A4 | |
| SCHEMBL8156803 | 0.89 | REN (0.55) | RENCYP3A4 | |
| SCHEMBL13250066 | 0.89 | REN (0.55) | RENCYP3A4 | |
| SCHEMBL4757561 | 0.88 | REN (0.40) | RENCYP3A4KMT2A | |
| SCHEMBL3115866 | 0.81 | REN (0.57) | RENCYP3A4 | |
| SCHEMBL3114688 | 0.81 | REN (0.57) | RENCYP3A4 | |
| SCHEMBL3120809 | 0.81 | REN (0.57) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |