Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112304 | 0.89 | REN (0.41) | RENCYP3A4 | |
| SCHEMBL4757725 | 0.89 | REN (0.41) | RENCYP3A4 | |
| SCHEMBL4757563 | 0.88 | REN (0.44) | RENCYP3A4 | |
| SCHEMBL3115866 | 0.85 | REN (0.57) | RENCYP3A4 | |
| SCHEMBL3114688 | 0.85 | REN (0.57) | RENCYP3A4 | |
| SCHEMBL3120809 | 0.85 | REN (0.57) | RENCYP3A4 | |
| SCHEMBL8162177 | 0.84 | REN (0.66) | RENCYP3A4 | |
| SCHEMBL13250058 | 0.84 | REN (0.66) | RENCYP3A4 | |
| SCHEMBL3114574 | 0.80 | REN (0.47) | RENCYP3A4 | |
| SCHEMBL3113055 | 0.80 | REN (0.47) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |