Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757882 | 0.81 | ERN1 (0.45) | HMGB1CXCL12ERN1ALDH1A1POLB | |
| SCHEMBL4755647 | 0.81 | HCAR2 (0.38) | HMGB1CXCL12ERN1ALDH1A1POLB | |
| SCHEMBL4755047 | 0.80 | MAPT (0.43) | HMGB1CXCL12ERN1TDP1MAPT | |
| SCHEMBL28661953 | 0.73 | HMGB1 (0.41) | HMGB1CXCL12ALDH1A1POLBTDP1 | |
| SCHEMBL28739771 | 0.73 | ERN1 (0.48) | ERN1MAPTCYP3A4SRC | |
| SCHEMBL7050926 | 0.73 | HMGB1 (0.49) | HMGB1CXCL12ALDH1A1TDP1MAPT | |
| SCHEMBL18677494 | 0.72 | HMGB1 (0.47) | HMGB1CXCL12ALDH1A1TDP1HSD17B10 | |
| SCHEMBL28675093 | 0.72 | HMGB1 (0.47) | HMGB1CXCL12ALDH1A1TDP1MAPT | |
| SCHEMBL12488947 | 0.71 | GABRP (0.41) | HMGB1CXCL12ERN1ALDH1A1POLB | |
| SCHEMBL4756893 | 0.71 | TDP1 (0.46) | HMGB1CXCL12ERN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879661-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | claimed |
| WO-2006119821-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | claimed |