Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756893 | 0.81 | TDP1 (0.46) | ERN1HMGB1CXCL12TDP1ALDH1A1 | |
| SCHEMBL4757726 | 0.81 | HMGB1 (0.40) | ERN1HMGB1CXCL12TDP1ALDH1A1 | |
| SCHEMBL11557582 | 0.77 | ERN1 (0.67) | ERN1HMGB1CXCL12TDP1ALDH1A1 | |
| SCHEMBL27945834 | 0.77 | ERN1 (0.46) | ERN1HMGB1CXCL12TDP1ALDH1A1 | |
| SCHEMBL2457983 | 0.75 | ERN1 (0.52) | ERN1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL31315038 | 0.75 | HMGB1 (0.52) | HMGB1CXCL12TDP1ALDH1A1MAPT | |
| SCHEMBL11083912 | 0.75 | THRB (0.48) | HMGB1CXCL12TDP1ALDH1A1MAPT | |
| SCHEMBL8830153 | 0.75 | HMGB1 (0.52) | HMGB1CXCL12TDP1ALDH1A1MAPT | |
| SCHEMBL4755647 | 0.75 | HCAR2 (0.38) | ERN1HMGB1CXCL12TDP1ALDH1A1 | |
| SCHEMBL10111663 | 0.74 | ERN1 (0.39) | ERN1TDP1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879661-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | claimed |
| WO-2006119821-A1 | AGENT FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | claimed |