SCHEMBL4757873

SCHEMBL4757873

O=C(O)C1C2CC(C(Br)C2Br)C1C(=O)OC(=O)C1C2CC(C(Br)C2Br)C1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.46
POLB P06746 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6321813 0.87 POLB (0.44) MAPK1POLBTDP1TSHR
SCHEMBL13216614 0.87 MAPK1 (0.55) MAPK1POLBTDP1TSHR
SCHEMBL3025318 0.87 MAPK1 (0.55) MAPK1POLBTDP1TSHR
SCHEMBL432536 0.71 POLB (0.57) MAPK1POLBTDP1TSHR
SCHEMBL11855992 0.71 POLB (0.30) POLBTDP1
SCHEMBL12732743 0.70 PPM1B (0.52) POLBTDP1
SCHEMBL3782939 0.69 GABRR1 (0.33) POLBTDP1
SCHEMBL3779680 0.69 POLB (0.33) POLBTDP1
SCHEMBL15400430 0.69 POLB (0.35) POLBTDP1TSHR
SCHEMBL4344019 0.69 POLB (0.35) POLBTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008106334-A2 FLAME RETARDED STYRENIC POLYMER FOAMS AND FOAM PRECURSORS ALBEMARLE CORPORATION (US) 2008-09-04 WO disclosed