Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.59 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325511 | 0.83 | EGLN1 (0.61) | EGLN1FTOBBOX1KDM5BKDM2A | |
| SCHEMBL523235 | 0.82 | EGLN1 (0.70) | EGLN1FTOBBOX1KDM5BKDM2A | |
| SCHEMBL522718 | 0.81 | EGLN1 (0.69) | EGLN1FTOBBOX1KDM5BKDM2A | |
| SCHEMBL4757084 | 0.81 | EGLN1 (0.61) | EGLN1FTOBBOX1KDM5BKDM2A | |
| SCHEMBL5027666 | 0.79 | EGLN1 (0.68) | EGLN1FTOBBOX1KDM6BTHRA | |
| SCHEMBL5315453 | 0.79 | EGLN1 (0.61) | EGLN1FTOBBOX1KDM5BKDM2A | |
| SCHEMBL4411746 | 0.76 | EGLN1 (0.61) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL4407707 | 0.76 | EGLN1 (0.54) | EGLN1FTOBBOX1KDM5BKDM2A | |
| SCHEMBL522241 | 0.75 | EGLN1 (0.57) | EGLN1FTOBBOX1KDM5BKDM2A | |
| SCHEMBL29390250 | 0.75 | EGLN1 (1.00) | EGLN1FTOBBOX1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009002533-A1 | INFLAMMATORY BOWEL DISEASE THERAPIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2008-12-31 | — | — | WO | disclosed |